The 40 Year Old Virgin (2005) Review
Andy Stitzer (Steve Carell) doesn't have too many friends. He lives alone in an apartment filled with all sorts of collectible dolls and comic books and video games and all the sorts of things you might have if you lived on your own until you were 40. He tries to pass himself off as one of the guys, but they all suspect something just isn't right, and they just can't put their finger on it. They suspect he is gay or a serial killer. But it's something much worse.
You see, Andy is a virgin. So the guys at the store make a pact to try and take care of Andy's little "problem". In fact, everyone tries to take care of Andy's problem.